1
00:00:00,000 --> 00:00:02,900
Hello, ladies and gents Robert 
Sykes keto Savage.com. 

2
00:00:02,900 --> 00:00:06,100
And today I have special, guest 
David Krantz on the line. 

3
00:00:06,400 --> 00:00:09,500
We dive deep into genetics, we 
talk about our genetics, we 

4
00:00:09,500 --> 00:00:12,900
talked about how those genetic 
predispositions, can be changed 

5
00:00:12,900 --> 00:00:15,800
and turned on and off via our 
environmental factors. 

6
00:00:16,100 --> 00:00:18,600
We talked about epigenetics and 
how the decisions we make an 

7
00:00:18,600 --> 00:00:20,000
impact. 
Our Offspring. 

8
00:00:20,200 --> 00:00:24,500
We talk about the inner 
cannabinoid system, a subject 

9
00:00:24,500 --> 00:00:27,700
that I know very little about 
but he really opened my eyes as 

10
00:00:27,700 --> 00:00:29,800
to how that can impact 
everything we do. 

11
00:00:30,000 --> 00:00:34,200
Do how certain Gene Expressions 
can impact, you know, our 

12
00:00:34,500 --> 00:00:39,200
receptiveness of THC CBD and all
the different interconnected 

13
00:00:39,200 --> 00:00:42,900
cannabinoids and the whole full 
spectrum, second speaks right? 

14
00:00:42,900 --> 00:00:45,500
I don't know that much about it 
but I really enjoyed the 

15
00:00:45,508 --> 00:00:49,200
conversation. 
David is a very smart guy and I 

16
00:00:49,200 --> 00:00:52,700
learned a ton and you will too. 
So without further Ado sit back 

17
00:00:52,700 --> 00:00:55,100
relax and enjoy the podcast with
Dave currents. 

18
00:01:04,800 --> 00:01:06,000
Dave, will laugh. 
How are you, man? 

19
00:01:07,200 --> 00:01:09,400
I'm doing well. 
Robert, thanks for having me on.

20
00:01:09,500 --> 00:01:11,000
Absolutely thanks for taking the
time. 

21
00:01:11,400 --> 00:01:15,000
So you reach that Nanny on me. 
And I started kind of digging 

22
00:01:15,000 --> 00:01:17,200
into your background and kind of
what you've been up to what your

23
00:01:17,200 --> 00:01:20,500
what your focus is. 
And I was immediately drawn to, 

24
00:01:20,500 --> 00:01:22,000
you know, all the genetic work 
you're doing. 

25
00:01:22,300 --> 00:01:24,700
I just kind of want to dive into
some background, kind of give us

26
00:01:24,700 --> 00:01:26,700
a little bio one. 
What got you to the health and 

27
00:01:26,700 --> 00:01:28,000
nutrition space in the first 
place? 

28
00:01:28,000 --> 00:01:31,100
And then kind of dive into the 
Weeds on everything genetics and

29
00:01:31,100 --> 00:01:33,700
all that, that entails. 
Yeah, sure. 

30
00:01:33,700 --> 00:01:37,600
So yeah. 
I like a lot of people Myself in

31
00:01:37,600 --> 00:01:40,000
the health and wellness space 
because I had to figure out my 

32
00:01:40,000 --> 00:01:43,900
own health issues. 
And you know, in my early 20s, I

33
00:01:43,900 --> 00:01:46,800
started having some weird health
problems crop up. 

34
00:01:47,000 --> 00:01:49,700
And at this time, I was a 
touring musician actually. 

35
00:01:49,900 --> 00:01:53,400
And I was living you know pretty
late late, late night lifestyle,

36
00:01:53,400 --> 00:01:57,000
I would say, sometimes being out
until 4:00 5:00 in the morning 

37
00:01:57,600 --> 00:02:00,500
playing gigs and just do and 
doing the thing. 

38
00:02:00,800 --> 00:02:05,000
And I really hadn't given a lot 
of consideration to what I was 

39
00:02:05,000 --> 00:02:08,000
doing with my health and then I 
started having these issues 

40
00:02:08,000 --> 00:02:11,200
where I would pass out randomly,
like I would just buy the real 

41
00:02:11,200 --> 00:02:12,600
couple times where I woke up on 
the floor. 

42
00:02:12,600 --> 00:02:16,500
I didn't know what had happened 
and I was experiencing some 

43
00:02:16,500 --> 00:02:20,400
pretty severe nervous system 
dysfunction and I went to a 

44
00:02:20,400 --> 00:02:24,900
couple doctors well-trained 
cardiologists and people that, 

45
00:02:25,200 --> 00:02:27,500
you know, I was hoping they 
could give me some answers and 

46
00:02:27,500 --> 00:02:29,700
they really did and they really 
didn't have much for me. 

47
00:02:29,900 --> 00:02:33,300
They were basically like well, 
in an hour eyes, you're young 

48
00:02:33,300 --> 00:02:35,400
and healthy, you're just gonna 
have to learn how to deal with 

49
00:02:35,400 --> 00:02:40,700
this and Kind of embarked on the
path of figuring out how to 

50
00:02:40,700 --> 00:02:42,900
affect my biology in whatever 
way I could. 

51
00:02:42,900 --> 00:02:47,400
And I got really into one of the
biohacking world and that space 

52
00:02:47,400 --> 00:02:52,100
and found keto around that time 
actually and started making some

53
00:02:52,100 --> 00:02:55,700
changes and saw some improvement
in a lot of areas that I 

54
00:02:55,700 --> 00:02:59,200
actually didn't expect. 
You know, I was my cognitive 

55
00:02:59,200 --> 00:03:03,300
function came online in a way 
that I never experienced and 

56
00:03:03,800 --> 00:03:06,700
then this really interesting 
synchronicity happened. 

57
00:03:06,900 --> 00:03:10,100
Where I had been listening to 
this one podcast. 

58
00:03:10,100 --> 00:03:12,800
I think I listened to probably 
about 60 episodes of it. 

59
00:03:12,800 --> 00:03:15,700
I listen to every single one 
that was out there by this 

60
00:03:15,700 --> 00:03:20,700
doctor named Dan stickler, who 
was an expert in genetics and 

61
00:03:20,700 --> 00:03:26,200
epigenetics and using genetics 
to predict what diets work well,

62
00:03:26,200 --> 00:03:30,200
and that kind of thing. 
And I was I was I was, you know,

63
00:03:30,200 --> 00:03:32,100
I found this guy and I just 
thought there's no one else 

64
00:03:32,100 --> 00:03:35,000
really talking about this. 
And then, I took a walk on my 

65
00:03:35,000 --> 00:03:38,300
lunch break one day at work. 
I realize that the logo of this 

66
00:03:38,300 --> 00:03:42,900
podcast was literally on the 
building next door to me and it 

67
00:03:42,900 --> 00:03:45,200
turned out that the doctor 
actually had an office right 

68
00:03:45,200 --> 00:03:46,500
next door to where I was 
working. 

69
00:03:46,800 --> 00:03:49,600
And I initially just made an 
appointment because I wanted 

70
00:03:49,600 --> 00:03:52,700
some blood work done and it 
turned out, they're actually 

71
00:03:52,700 --> 00:03:55,700
looking to hire someone who had 
a background in audio, 

72
00:03:55,700 --> 00:03:58,900
engineering and music because 
they were wanting to create some

73
00:03:58,900 --> 00:04:02,000
meditation programs and 
brainwave entrainment programs. 

74
00:04:02,700 --> 00:04:05,100
And I was like, all right, yeah,
this is perfect. 

75
00:04:05,100 --> 00:04:08,600
Here is the life path thing. 
NG Just Happening unfolding in 

76
00:04:08,600 --> 00:04:10,700
front of me, so I started 
working for them and right 

77
00:04:10,700 --> 00:04:13,800
around the same time, this 
doctor developed a training 

78
00:04:13,800 --> 00:04:18,000
program for other coaches and 
doctors with his method of using

79
00:04:18,000 --> 00:04:20,800
genetics and I was in the right 
place at the right time. 

80
00:04:20,800 --> 00:04:25,600
He asked me if I would help beta
test this training program and I

81
00:04:25,600 --> 00:04:28,600
actually said, No, at first, I 
was like, hey I'm a musician. 

82
00:04:28,600 --> 00:04:31,000
I'm not really a health 
practitioner like, I know I've 

83
00:04:31,000 --> 00:04:33,700
kind of figured this stuff out 
for myself, but wasn't really 

84
00:04:33,700 --> 00:04:34,900
confident to do it for other 
people. 

85
00:04:34,900 --> 00:04:39,900
And you kind of hold my arm a 
little bit and tried to convince

86
00:04:39,900 --> 00:04:44,400
me and I finally said yes and 
ended up, taking this training 

87
00:04:44,400 --> 00:04:47,800
with him a couple times before 
he made a public and found, you 

88
00:04:47,800 --> 00:04:50,500
know, found myself as kind of an
early adopter of this system 

89
00:04:50,900 --> 00:04:54,100
that really launched me into 
doing this work for other people

90
00:04:54,100 --> 00:04:57,000
and found that I really had an 
affinity Affinity to it and 

91
00:04:57,000 --> 00:05:00,500
really enjoyed it and was able 
to take what I had learned with 

92
00:05:00,500 --> 00:05:04,500
my own health issues and apply 
them to other people and really,

93
00:05:04,700 --> 00:05:06,700
you know, help people move 
towards Optimal Health and their

94
00:05:06,700 --> 00:05:09,300
own Way, catch again, she had 
genetics. 

95
00:05:09,600 --> 00:05:12,900
Genetics have always fascinated 
me because it's something 

96
00:05:12,900 --> 00:05:15,500
that's, you know, you can't 
innately change. 

97
00:05:15,500 --> 00:05:18,500
Your genetic background but you 
can like turn these different 

98
00:05:18,500 --> 00:05:21,400
genes on based off of your 
environmental factors. 

99
00:05:21,500 --> 00:05:24,400
And, you know, that that's 
that's incredibly fascinating in

100
00:05:24,400 --> 00:05:26,100
itself. 
But then this whole concept of 

101
00:05:26,100 --> 00:05:29,700
epigenetics and how, you know, 
what you do in your day-to-day 

102
00:05:29,700 --> 00:05:34,200
can have a direct impact on your
Offspring and their offspring 

103
00:05:34,200 --> 00:05:37,700
for years to come like that, 
that it really Peel the layers 

104
00:05:37,700 --> 00:05:39,900
back and it makes you 
responsible for anything you're 

105
00:05:39,900 --> 00:05:42,500
doing in the day-to-day. 
Yeah, absolutely. 

106
00:05:42,500 --> 00:05:46,600
And it's, it's simultaneously. 
A really empowering perspective 

107
00:05:46,600 --> 00:05:50,200
for some people. 
And in another way, it can make 

108
00:05:50,200 --> 00:05:52,800
people feel guilty about not 
doing enough right right before,

109
00:05:52,800 --> 00:05:54,200
like they had kids or something 
like that. 

110
00:05:54,200 --> 00:05:57,300
So I think it's an important 
thing to really think about how 

111
00:05:57,300 --> 00:05:59,900
to frame it. 
Well, for people and give people

112
00:05:59,900 --> 00:06:02,600
the opportunity to like you 
said, no that they can change 

113
00:06:02,600 --> 00:06:06,000
their genetic expression. 
Which in a lot of ways can 

114
00:06:06,000 --> 00:06:09,700
override, Add some of the 
genetic predispositions that we 

115
00:06:09,700 --> 00:06:11,300
used to think we're way more 
fixed. 

116
00:06:11,400 --> 00:06:15,700
So that's what I do with clients
is help them really understand 

117
00:06:16,000 --> 00:06:19,200
how their bodies are wired and 
then what are the environmental 

118
00:06:19,200 --> 00:06:21,900
variables that they can be 
matched up to that? 

119
00:06:21,900 --> 00:06:25,700
Will really allow them to thrive
in a way that, you know, having 

120
00:06:25,700 --> 00:06:28,900
that information might, you 
know, might not be available to 

121
00:06:28,900 --> 00:06:31,300
you without really picking that 
apart. 

122
00:06:31,600 --> 00:06:35,200
When you're working with people,
what is their initial like just 

123
00:06:35,200 --> 00:06:38,500
Outlook towards unix-like, do 
they This kind of, you know, 

124
00:06:38,500 --> 00:06:41,400
it's just my jeans. 
I have no control over it too, 

125
00:06:41,400 --> 00:06:44,400
kind of mentality and it just is
what it is or do they feel like 

126
00:06:44,400 --> 00:06:47,200
they can actually, you know, 
sink their teeth into it and and

127
00:06:47,200 --> 00:06:50,000
have a direct impact? 
Well, a lot of the people that 

128
00:06:50,000 --> 00:06:54,500
find me are already aware of the
idea that they can have that 

129
00:06:54,500 --> 00:06:57,000
direct impact. 
I don't work with a ton of 

130
00:06:57,000 --> 00:06:59,300
people that have that fixed 
mindset. 

131
00:06:59,300 --> 00:07:03,200
I very selectively. 
Look for people as clients that 

132
00:07:03,200 --> 00:07:06,100
have that malleability and 
understanding. 

133
00:07:06,300 --> 00:07:11,500
But I Think there's always a few
things, that psychologically 

134
00:07:11,500 --> 00:07:15,200
we're kind of holding onto 
around, you know, I'm going to 

135
00:07:15,207 --> 00:07:17,300
inherit this or I'm going to 
inherit that. 

136
00:07:17,300 --> 00:07:21,000
So, you know, I would say that 
my clients predominantly come 

137
00:07:21,000 --> 00:07:23,800
with the idea that they have 
control over their health, but 

138
00:07:23,800 --> 00:07:27,900
then exploring what that means. 
In a deeper context, is usually 

139
00:07:27,900 --> 00:07:31,800
really interesting because it 
can often lead to realizing, 

140
00:07:31,800 --> 00:07:33,800
hey, I have more control than I 
actually thought. 

141
00:07:34,300 --> 00:07:37,000
Can you take a moment to kind of
shed some light on how Much 

142
00:07:37,000 --> 00:07:38,400
control. 
We actually have a mean. 

143
00:07:38,600 --> 00:07:42,200
We can't change our parents 
obviously, but, you know, just 

144
00:07:42,200 --> 00:07:45,600
kind of dive into how our 
environmental factors can turn 

145
00:07:45,600 --> 00:07:47,200
on or off these different Gene 
expressions. 

146
00:07:47,200 --> 00:07:49,500
And I feel like hearing that 
people like at the listen to 

147
00:07:49,508 --> 00:07:53,300
this, they just haven't no clue 
as to what they can control. 

148
00:07:53,300 --> 00:07:56,000
Just simply giving them some 
context I think would be would 

149
00:07:56,000 --> 00:07:58,200
be beneficial. 
Yeah, absolutely. 

150
00:07:58,200 --> 00:08:01,000
And maybe we should just do 
general definition of 

151
00:08:01,000 --> 00:08:03,800
epigenetics just just just 
start. 

152
00:08:03,800 --> 00:08:06,900
Yeah. 
So you know when I was Has 

153
00:08:06,900 --> 00:08:11,000
taught biology and high school 
class, you know, I we learned 

154
00:08:11,000 --> 00:08:15,200
the central dogma of biology, 
which was the truth for many, 

155
00:08:15,200 --> 00:08:17,100
many years. 
And it still is part of the 

156
00:08:17,100 --> 00:08:19,100
truth. 
But at this is the idea that 

157
00:08:19,100 --> 00:08:23,500
your genes code for proteins and
those proteins code for traits. 

158
00:08:23,800 --> 00:08:27,700
And this idea leads to people 
thinking that okay these traits 

159
00:08:27,700 --> 00:08:29,600
are fixed, right? 
Your you have this code, it 

160
00:08:29,600 --> 00:08:32,799
doesn't change your hair color 
is going to be a certain color. 

161
00:08:32,799 --> 00:08:34,299
Your eyes are going to be a 
certain color. 

162
00:08:34,299 --> 00:08:38,500
Your disease risks are going to 
just kind of be If they are and 

163
00:08:38,500 --> 00:08:42,900
then really the first inklings 
of this happened around 30 years

164
00:08:42,900 --> 00:08:45,600
ago or so. 
And in the past, 15 or 20, 

165
00:08:45,600 --> 00:08:48,400
there's been an absolute 
revolution in the understanding 

166
00:08:48,400 --> 00:08:52,200
of what genetics are really 
doing and this is epigenetics, 

167
00:08:52,200 --> 00:08:56,200
which is talking about these 
markers that get put on to the 

168
00:08:56,200 --> 00:08:58,500
genetic code. 
That, like, you said, either, 

169
00:08:58,500 --> 00:09:02,600
cause genes to get turned on or 
get turned off and you can 

170
00:09:02,600 --> 00:09:05,600
imagine it kind of like each one
of your jeans. 

171
00:09:06,000 --> 00:09:07,800
Kind of has like, a different 
Dimmer switch on it. 

172
00:09:07,800 --> 00:09:11,500
And when that, when you 
encounter something in the 

173
00:09:11,500 --> 00:09:14,100
environment, you put something 
in your body, you're exposed to 

174
00:09:14,100 --> 00:09:16,600
stress. 
Pretty much anything, you can 

175
00:09:16,600 --> 00:09:20,000
imagine in your daily life. 
Your body is responding to that 

176
00:09:20,000 --> 00:09:22,700
and going maybe we should make 
more of this certain stress 

177
00:09:22,700 --> 00:09:27,400
hormone to respond to the 
stress, or maybe we should 

178
00:09:27,400 --> 00:09:29,700
create more of this 
neurotransmitter in order to 

179
00:09:29,700 --> 00:09:33,200
respond to the situation. 
And so all of these biochemical 

180
00:09:33,200 --> 00:09:37,700
reactions in the body have these
genetic Opponents to them. 

181
00:09:38,000 --> 00:09:44,700
And what they found is, some 
things are relatively stable but

182
00:09:44,700 --> 00:09:48,300
a lot of the things that we 
experience are very adaptable 

183
00:09:48,300 --> 00:09:51,300
and very changeable. 
And the predominant view right 

184
00:09:51,300 --> 00:09:57,500
now, is that our genes are less.
The say the, the blueprint for 

185
00:09:57,500 --> 00:10:00,600
our bodies like we thought, then
they're more the environmental 

186
00:10:00,600 --> 00:10:04,000
sensors that change that 
blueprint, dynamically. 

187
00:10:04,600 --> 00:10:09,900
And so what What I mean by this 
is like you know people used to 

188
00:10:09,900 --> 00:10:12,800
think that over going to find 
the depression Gene you know 

189
00:10:12,800 --> 00:10:16,400
we're going to find this Gene 
that makes people more depressed

190
00:10:16,800 --> 00:10:22,000
or we're going to find the the 
the heart disease Gene and very 

191
00:10:22,000 --> 00:10:24,800
quickly. 
Once we map the human genome, we

192
00:10:24,800 --> 00:10:27,100
realize, okay there this way 
more complex than that. 

193
00:10:27,200 --> 00:10:28,800
So then they started looking at 
okay. 

194
00:10:28,800 --> 00:10:31,500
Maybe we can look at you know 50
different genes that all 

195
00:10:31,500 --> 00:10:34,000
combined together and those are 
going to be the set of 

196
00:10:34,000 --> 00:10:36,700
depression genes and the started
looking. 

197
00:10:36,800 --> 00:10:37,900
Like that and realize. 
Okay? 

198
00:10:37,900 --> 00:10:39,600
It's actually more complex than 
that. 

199
00:10:40,300 --> 00:10:45,100
And really what it is is certain
genes create sensitivities to 

200
00:10:45,100 --> 00:10:48,600
the environment. 
So say someone has a variant 

201
00:10:48,600 --> 00:10:52,500
that might predispose them to 
depression if they're exposed to

202
00:10:52,500 --> 00:10:55,700
higher levels of stress at this 
particular time in their life 

203
00:10:55,700 --> 00:10:59,200
you know early childhood or they
might have a gene that 

204
00:10:59,200 --> 00:11:03,600
predisposes them to higher heart
disease risk but only if they're

205
00:11:03,700 --> 00:11:06,300
eating the wrong type of fat for
their body, right? 

206
00:11:06,300 --> 00:11:09,800
It's that new tits, the the 
environment Gene, interaction 

207
00:11:09,800 --> 00:11:12,700
that matters. 
So what that really means is 

208
00:11:13,200 --> 00:11:15,600
that if you kind of match 
yourself up with the right 

209
00:11:15,600 --> 00:11:19,800
environment so you have the 
hired, predisposition towards 

210
00:11:19,800 --> 00:11:22,200
depression. 
Well, if you do the things to 

211
00:11:22,200 --> 00:11:26,100
mitigate stress, you do the 
things to develop positive 

212
00:11:26,100 --> 00:11:30,400
relationships and you do the 
things that lower inflammation 

213
00:11:30,400 --> 00:11:32,900
in the body. 
And look at it from from all 

214
00:11:32,908 --> 00:11:35,900
these different layers. 
Then your risk of depression 

215
00:11:36,400 --> 00:11:39,600
might Sleepy lower than someone 
with the quote unquote, normal 

216
00:11:39,600 --> 00:11:42,900
variant of it and same thing 
with say heart disease. 

217
00:11:43,400 --> 00:11:47,600
If you match yourself up say you
have the some of the variants 

218
00:11:47,600 --> 00:11:51,100
that can create higher risk with
the wrong types of fat. 

219
00:11:51,700 --> 00:11:54,100
And you know, I think this is 
important for people listening 

220
00:11:54,200 --> 00:11:57,800
from a keto perspective. 
You know, you do match yourself 

221
00:11:57,800 --> 00:12:01,200
up with the correct types of fat
for your body then and you do 

222
00:12:01,200 --> 00:12:05,200
exercise and you lower 
inflammation, then your risk of 

223
00:12:05,200 --> 00:12:08,100
heart disease. 
You know probably will go down 

224
00:12:08,200 --> 00:12:11,100
significantly lower than someone
with the quote unquote, normal 

225
00:12:11,100 --> 00:12:14,300
normal variant. 
So people with the less 

226
00:12:14,300 --> 00:12:17,200
sensitive variants might be able
to get away with more so to 

227
00:12:17,200 --> 00:12:20,100
speak in life. 
But people with the more 

228
00:12:20,100 --> 00:12:24,100
sensitive ones, they're actually
can be advantages to that when 

229
00:12:24,100 --> 00:12:28,100
you're in the right environment,
in the right setting, putting 

230
00:12:28,100 --> 00:12:30,900
the right things in your body. 
And so, one of the things I 

231
00:12:30,908 --> 00:12:32,800
love, I love to stress with my 
clients. 

232
00:12:32,800 --> 00:12:36,000
Is that, you know, there really 
aren't good or bad genes. 

233
00:12:36,300 --> 00:12:38,400
They're Just genes that are 
suited for different 

234
00:12:38,400 --> 00:12:39,900
environments. 
Yeah. 

235
00:12:39,900 --> 00:12:42,800
That to me makes a lot of sense 
and I feel like a lot of people 

236
00:12:43,300 --> 00:12:47,200
you know, they they try and base
everything off of what their 

237
00:12:47,200 --> 00:12:50,500
genes are telling them that 
they're like a 23andMe test and 

238
00:12:50,500 --> 00:12:53,200
they'll base all their 
environmental factors off of 

239
00:12:53,300 --> 00:12:55,100
those, you know, 
predispositions. 

240
00:12:55,100 --> 00:12:58,400
But I feel like it's just so 
much more complex than you can. 

241
00:12:58,400 --> 00:13:00,700
You can based off of anyone 
tells like really have to dive 

242
00:13:00,700 --> 00:13:04,100
in deep. 
And there's, I mean, I don't 

243
00:13:04,100 --> 00:13:06,900
know what the gray of variance 
there is between how much These 

244
00:13:06,900 --> 00:13:10,400
environmental factors have on 
your epigenetic factors going 

245
00:13:10,400 --> 00:13:13,200
forward. 
But I feel like it's empowering 

246
00:13:13,200 --> 00:13:16,800
to know and that what your jeans
are is not your end all be all 

247
00:13:16,800 --> 00:13:20,800
like you can have environmental 
fluctuations that you have 

248
00:13:20,800 --> 00:13:24,000
complete control over for the 
most part that can have a 

249
00:13:24,000 --> 00:13:26,800
positive or negative effect on 
whatever your Gene 

250
00:13:26,800 --> 00:13:28,600
predisposition is. 
Right. 

251
00:13:28,600 --> 00:13:30,800
Exactly. 
And and that's the trouble with 

252
00:13:30,800 --> 00:13:34,900
something like 23andMe or a lot 
of the other direct to Consumer 

253
00:13:34,900 --> 00:13:38,200
tests that you can go out and 
get Is that they don't usually 

254
00:13:38,200 --> 00:13:42,900
do a very good job of explaining
like, okay, you have a say 

255
00:13:42,900 --> 00:13:46,400
higher heart disease risk. 
Well, what are the the factors 

256
00:13:46,400 --> 00:13:49,200
that might change that, right? 
And 23andMe doesn't really 

257
00:13:49,200 --> 00:13:53,100
provide that information and it 
takes a lot of kind of higher 

258
00:13:53,100 --> 00:13:56,600
level of understanding to really
incorporate that. 

259
00:13:56,600 --> 00:13:59,800
And the other thing that's 
really important, like you said,

260
00:13:59,800 --> 00:14:03,900
in terms of the complexity is 
genes are not very good at 

261
00:14:03,900 --> 00:14:06,600
predicting the stuff on their 
own, what really? 

262
00:14:06,700 --> 00:14:10,200
Ders is the combination of 
understanding your genes and 

263
00:14:10,200 --> 00:14:13,000
then understanding what's 
expressing right now. 

264
00:14:13,200 --> 00:14:17,000
So if you go out and take a 
test, unless you're doing an 

265
00:14:17,000 --> 00:14:20,000
interview with someone who's 
running the tests and they know 

266
00:14:20,000 --> 00:14:22,500
about, you know, what's what's 
been your struggles? 

267
00:14:22,500 --> 00:14:26,500
What's your goals, are where 
you're at, you know, like adding

268
00:14:26,500 --> 00:14:30,800
that level of information really
gives you the ability to use the

269
00:14:30,800 --> 00:14:34,900
genes in a way that allows you 
to make much stronger 

270
00:14:34,900 --> 00:14:38,500
recommendations to say. 
Oh, You know, you've got some 

271
00:14:38,500 --> 00:14:40,800
penis pictures and Streaker Gene
to express like this. 

272
00:14:40,900 --> 00:14:44,100
They clearly are expressing in 
this way or they're not 

273
00:14:44,100 --> 00:14:46,300
expressing in this way. 
It maybe it's because you've 

274
00:14:46,300 --> 00:14:48,600
already done something, you 
know, in your life you've 

275
00:14:48,600 --> 00:14:50,800
already matched up some of these
environmental factors. 

276
00:14:51,200 --> 00:14:55,900
So the the real art of using 
this information, you know, just

277
00:14:55,900 --> 00:14:58,100
like a blood test. 
It's like you can go out and get

278
00:14:58,100 --> 00:15:00,200
a blood test online. 
But if you don't know how to 

279
00:15:00,200 --> 00:15:04,500
look at patterns, you know, like
looking at how different blood 

280
00:15:04,500 --> 00:15:07,300
markers, relate to other ones, 
you're going to Miss a lot of 

281
00:15:07,300 --> 00:15:11,600
the important information. 
So you know, I'm passionate 

282
00:15:11,600 --> 00:15:15,000
about like helping people use 
this information well, because 

283
00:15:15,000 --> 00:15:20,300
there's a lot of kind of 
half-assed, use of it out there 

284
00:15:20,300 --> 00:15:21,900
right now is the way I feel 
about it. 

285
00:15:22,300 --> 00:15:23,900
Yeah. 
And it's just interesting 

286
00:15:23,900 --> 00:15:29,000
because it it goes far beyond 
just like your, you know, direct

287
00:15:29,000 --> 00:15:30,600
environment effects. 
Like it goes to to 

288
00:15:30,600 --> 00:15:32,400
supplementation. 
For instance, some people are 

289
00:15:32,700 --> 00:15:35,400
going to be able to uptake 
caffeine and the body's gonna be

290
00:15:35,408 --> 00:15:38,600
able to use that. 
More so effectively than others 

291
00:15:38,600 --> 00:15:42,300
that have the improper, you 
know, gene expression for fully 

292
00:15:42,300 --> 00:15:46,100
utilizing caffeine intake. 
Absolutely. 

293
00:15:46,100 --> 00:15:50,700
And then one of the interesting 
things about that is a, you 

294
00:15:50,700 --> 00:15:54,100
know, there's most genes have 
multiple functions like the gene

295
00:15:54,100 --> 00:15:59,100
that codes for the breakdown of 
caffeine, that's you can kind of

296
00:15:59,100 --> 00:16:02,000
loosely classify people as like,
a fast or slow metabolizer 

297
00:16:02,000 --> 00:16:07,400
caffeine that same enzyme that 
that Gene codes for also breaks 

298
00:16:07,400 --> 00:16:10,800
down melatonin. 
So again, it's like, you know, 

299
00:16:10,800 --> 00:16:13,500
people think of like oh I've got
this low caffeine metabolism 

300
00:16:13,500 --> 00:16:15,000
like a you know that's a bad 
thing. 

301
00:16:15,300 --> 00:16:17,800
But there's actually an 
advantage to that from the 

302
00:16:17,800 --> 00:16:21,100
Melatonin perspective because 
you can carry higher levels of 

303
00:16:21,100 --> 00:16:23,300
melatonin and Night Longer 
throughout the night. 

304
00:16:23,300 --> 00:16:27,700
So, there's always these kind of
trade-offs in terms of how we're

305
00:16:27,700 --> 00:16:31,900
suited to the environment. 
I feel like this has become a 

306
00:16:31,908 --> 00:16:35,300
very, you know, quote-unquote 
Sexy Thing lately, like this 

307
00:16:35,300 --> 00:16:38,800
whole Gene, you know, expression
likely diving in that and I feel

308
00:16:38,800 --> 00:16:42,300
like because it's become so, so 
popularized, like you're saying,

309
00:16:42,300 --> 00:16:46,500
there's a lot of just really, 
you know, Ignorant informal 

310
00:16:46,500 --> 00:16:49,500
testing mechanisms out there 
that do not paint, the perfect 

311
00:16:49,500 --> 00:16:54,000
picture by a long shot because I
feel like I did one a while 

312
00:16:54,000 --> 00:16:55,400
back. 
And it was telling me that like 

313
00:16:55,400 --> 00:16:59,300
I would not be able to digest 
fat very well and I mean, it's 

314
00:16:59,300 --> 00:17:02,300
obviously not the case. 
So, like for anybody listen to 

315
00:17:02,308 --> 00:17:05,700
this, if they really want to 
dive in and kind of go the right

316
00:17:05,700 --> 00:17:08,599
path instead of just, you know, 
being led astray and, you know, 

317
00:17:08,599 --> 00:17:12,700
doing some random generic, you 
know, ignorant testing format, 

318
00:17:12,700 --> 00:17:16,599
what do you recommend for them? 
Yeah, you know, I recommend they

319
00:17:16,599 --> 00:17:18,300
work with a professional, you 
know. 

320
00:17:18,300 --> 00:17:23,000
I think it's it's nice that 
people can go out and get these 

321
00:17:23,000 --> 00:17:24,700
tests. 
But I'll tell you in terms of 

322
00:17:24,700 --> 00:17:29,300
the level of Education that it 
really takes two to know how to 

323
00:17:29,300 --> 00:17:31,700
integrate this information. 
I think it's really worth 

324
00:17:31,700 --> 00:17:34,600
working with a coach, or a 
Doctor Who's familiar with using

325
00:17:34,600 --> 00:17:36,400
this stuff. 
Because when you see something 

326
00:17:36,400 --> 00:17:39,100
on the test, like, okay, you 
know, you can't digest fat 

327
00:17:39,100 --> 00:17:43,600
really well. 
It's important to be able to 

328
00:17:43,600 --> 00:17:46,800
know what that Gene is. 
Is actually coding for the gene 

329
00:17:46,800 --> 00:17:49,700
itself. 
Probably is not coding for your 

330
00:17:49,700 --> 00:17:55,800
body ability to break down fats,
probably coding for a, you know,

331
00:17:55,800 --> 00:18:00,000
something like protease or 
lipase or something like that. 

332
00:18:00,000 --> 00:18:02,900
And then if you can look at how 
that's linked up to say, other 

333
00:18:02,900 --> 00:18:05,600
genes that also might influence 
that that's really helpful. 

334
00:18:05,600 --> 00:18:09,000
So you know, working with 
someone who kind of who can look

335
00:18:09,000 --> 00:18:10,600
at this. 
From a complex systems 

336
00:18:10,600 --> 00:18:13,700
perspective, I think is really 
the way to go and it's not to 

337
00:18:13,700 --> 00:18:16,000
say that you can't get. 
Formation on your own. 

338
00:18:16,000 --> 00:18:19,100
Like there's there's good 
information out there. 

339
00:18:19,300 --> 00:18:24,000
It's just a matter of you really
want to spend the time digging 

340
00:18:24,000 --> 00:18:26,800
deeper than what the kind of 
stock. 

341
00:18:27,200 --> 00:18:29,900
Top-level answers are four 
things, right? 

342
00:18:29,900 --> 00:18:33,700
So like getting you keys at 
23andMe to get like just the raw

343
00:18:33,700 --> 00:18:36,000
genetic data. 
But then linking up with an 

344
00:18:36,000 --> 00:18:38,500
expert that can actually go over
that data in a simulator for use

345
00:18:38,500 --> 00:18:41,200
key, right? 
I think that's really important 

346
00:18:41,200 --> 00:18:44,200
and I'll have so many people 
that come to me after they've 

347
00:18:44,200 --> 00:18:46,500
tried to figure this. 
Tough out on their own and like,

348
00:18:46,500 --> 00:18:49,100
you know, they get some 
information out of it but 

349
00:18:49,100 --> 00:18:51,900
eventually they go, how do I, 
what do I actually do with this 

350
00:18:51,900 --> 00:18:55,400
stuff? 
So you know, I see a lot of 

351
00:18:55,700 --> 00:18:59,600
opportunity for people that are 
interested in understanding 

352
00:18:59,600 --> 00:19:03,400
their genetics to work with 
someone who can give them a 

353
00:19:03,500 --> 00:19:07,000
higher level perspective on it. 
Have you ever interacted with 

354
00:19:07,100 --> 00:19:08,300
dr. 
Anthony J. 

355
00:19:10,400 --> 00:19:13,000
I know the name, but I don't 
think so. 

356
00:19:13,300 --> 00:19:16,200
He's a genetic Guru, as well him
down at the farm. 

357
00:19:16,200 --> 00:19:19,100
And we went over all of my data,
just incredibly smart 

358
00:19:19,100 --> 00:19:24,200
individual, but he's really 
opened my eyes to how like like 

359
00:19:24,200 --> 00:19:26,700
certain chemicals that we come 
in contact with, like, just 

360
00:19:26,700 --> 00:19:29,800
day-to-day household chemicals, 
like, certain Fabrics on the 

361
00:19:29,800 --> 00:19:33,000
clothes that we wear can have a,
an epigenetic effect on like, 

362
00:19:33,000 --> 00:19:34,500
are hormone levels and estrogen 
levels. 

363
00:19:34,500 --> 00:19:38,200
I had no idea that it went that 
deep but it's truly eye-opening.

364
00:19:38,200 --> 00:19:41,400
When you start going on, It'll 
absolutely when you look at 

365
00:19:41,400 --> 00:19:48,200
things like pcbs and BPA. 
And all of these common toxins 

366
00:19:48,200 --> 00:19:51,700
that are in Plastics, and like 
you said, household cleaners, 

367
00:19:51,700 --> 00:19:56,200
and beauty products and 
phthalates, you know, things 

368
00:19:56,200 --> 00:19:58,600
like that. 
Most of the toxic effects of 

369
00:19:58,600 --> 00:20:02,500
those things are happening on 
the epigenetic level, and 

370
00:20:02,800 --> 00:20:08,200
they're causing for example, 
with something like BPA, that's 

371
00:20:08,200 --> 00:20:11,400
an endocrine disruptor. 
Disruptor, it's causing genetic 

372
00:20:11,400 --> 00:20:14,700
it causing genetic expression 
changes to the genes that 

373
00:20:14,700 --> 00:20:17,100
control hormones like 
testosterone or estrogen. 

374
00:20:17,500 --> 00:20:23,300
So it does go really deep. 
It is kind of the deepest layers

375
00:20:23,300 --> 00:20:26,100
there are and and this is also 
something that you know you 

376
00:20:26,100 --> 00:20:30,600
mentioned before around the 
transmission of this to Future 

377
00:20:30,600 --> 00:20:33,700
Generations. 
It's not that we're just 

378
00:20:33,700 --> 00:20:38,800
transmitting the chemicals 
themselves in terms of you know 

379
00:20:39,400 --> 00:20:42,600
Stored in spinal fluid or 
whatever. 

380
00:20:42,700 --> 00:20:44,200
You know, we're actually 
transferring the chemicals 

381
00:20:44,200 --> 00:20:47,500
physically. 
We're often transferring the 

382
00:20:47,500 --> 00:20:52,100
epigenetic effects of those 
toxins and chemicals that then 

383
00:20:52,100 --> 00:20:55,300
Mark the next Generations genes 
in a similar way. 

384
00:20:55,600 --> 00:20:59,600
So we're really talking about 
when we're talking about getting

385
00:20:59,600 --> 00:21:03,700
rid of environmental toxins were
talking about the toxins 

386
00:21:03,700 --> 00:21:06,200
themselves but also the residual
effects of them as well. 

387
00:21:07,000 --> 00:21:08,900
ENC this, I mean this is just 
incredible. 

388
00:21:09,000 --> 00:21:12,500
Fencing and I don't know, I 
don't know this information very

389
00:21:12,500 --> 00:21:15,100
well at all. 
But you know, people just assume

390
00:21:15,100 --> 00:21:19,100
that, you know, what their 
genetics are is simply that they

391
00:21:19,100 --> 00:21:21,200
have no control over them. 
And then any, you know, 

392
00:21:21,200 --> 00:21:23,300
offspring that have going 
forward that mean, it just kind 

393
00:21:23,300 --> 00:21:27,000
of, it is what it is, but like 
to really drill down into this 

394
00:21:27,000 --> 00:21:29,800
and see how your lifestyle 
factors and decisions, you know,

395
00:21:29,800 --> 00:21:33,100
whether you're drinking smoking 
training, sleeping, like all 

396
00:21:33,100 --> 00:21:36,800
these things can have a direct 
epigenetic effect on on your 

397
00:21:36,900 --> 00:21:40,400
lineage. 
It really Lee makes you or 

398
00:21:40,400 --> 00:21:43,000
should make you open your eyes 
to the fact that you, you have 

399
00:21:43,000 --> 00:21:45,900
responsibility over this and 
like you owe it to your kids 

400
00:21:46,300 --> 00:21:48,100
sake. 
I've nothing else to make sure 

401
00:21:48,100 --> 00:21:50,900
you get your shit together for 
lack of a better word, right? 

402
00:21:50,900 --> 00:21:53,500
Absolutely. 
And I'll try to look at it even 

403
00:21:53,500 --> 00:21:56,700
on a more Global level like from
the whole species perspective at

404
00:21:56,700 --> 00:22:04,000
this point, like are we gonna be
the carriers of The genetics and

405
00:22:04,000 --> 00:22:07,400
epigenetics that are going to 
make our species sicker and 

406
00:22:07,400 --> 00:22:09,200
sicker and more depressed and 
fatter. 

407
00:22:09,200 --> 00:22:13,000
Or we going to take the 
accountability that we have and 

408
00:22:13,000 --> 00:22:17,400
try and shift that and like you 
know this isn't a metaphorical 

409
00:22:17,400 --> 00:22:21,800
thing at all like there's not a 
tremendous amount of studies 

410
00:22:21,800 --> 00:22:26,400
because it's hard to look at 
generational effects in a 

411
00:22:26,400 --> 00:22:28,700
rigorous controlled kind of way 
in humans. 

412
00:22:28,700 --> 00:22:32,400
I mean in and mice there's 
tremendous. 

413
00:22:32,600 --> 00:22:35,200
And a studies that show the 
effects of this transmission. 

414
00:22:35,600 --> 00:22:40,000
But there are a few instances 
instances where there's been say

415
00:22:40,000 --> 00:22:42,700
world events that you can go 
back and track. 

416
00:22:42,700 --> 00:22:44,500
What happened in future 
Generations. 

417
00:22:44,500 --> 00:22:47,500
Like there's a there's this kind
of archetypal example. 

418
00:22:48,200 --> 00:22:52,700
They called The Dutch hunger 
famine where in World War Two 

419
00:22:52,700 --> 00:22:56,400
and area of Holland was 
blockaded from getting food for 

420
00:22:56,400 --> 00:23:00,300
about six months and there was 
widespread famine in this area 

421
00:23:00,700 --> 00:23:05,400
and what They found is that 
women that were pregnant and at 

422
00:23:05,400 --> 00:23:09,100
that time depending on whether 
they're in the first second or 

423
00:23:09,108 --> 00:23:14,000
third trimester, when they had 
limited food resources, their 

424
00:23:14,000 --> 00:23:18,400
kids would have different health
effects. 

425
00:23:18,400 --> 00:23:21,800
Like some had higher propensity 
for obesity like way higher than

426
00:23:21,800 --> 00:23:26,000
average, some had higher 
propensity for type 2 diabetes, 

427
00:23:26,000 --> 00:23:30,800
way higher than average and some
actually had propensity to be 

428
00:23:30,800 --> 00:23:35,700
really thin and it Ended on what
phase of pregnancy that they 

429
00:23:35,700 --> 00:23:40,600
were kind of starved in and 
beyond that. 

430
00:23:40,600 --> 00:23:43,300
They've actually tracked, 
grandchildren and found that 

431
00:23:43,300 --> 00:23:48,100
those effects are passed on to 
grandchildren as well. 

432
00:23:48,400 --> 00:23:50,300
So and they're not totally 
linear. 

433
00:23:50,300 --> 00:23:53,600
It's like the sometimes things 
will skip a generation or only 

434
00:23:53,600 --> 00:23:55,700
be president in males versus 
females. 

435
00:23:56,600 --> 00:24:00,000
And you see this also in 
children and grandchildren of 

436
00:24:00,000 --> 00:24:03,300
Holocaust Survivors, which 
actually is One of the big 

437
00:24:03,700 --> 00:24:06,000
reasons why I was so fascinated 
with this information at first 

438
00:24:06,000 --> 00:24:09,800
my grandparents on my mom's side
were in concentration camps in 

439
00:24:09,800 --> 00:24:15,500
Poland and so I'm a I'm part of 
what I'm about to describe in 

440
00:24:15,500 --> 00:24:19,800
the study is that children and 
grandchildren of Holocaust 

441
00:24:19,800 --> 00:24:23,700
Survivors tend to have 
heightened stress responses and 

442
00:24:23,700 --> 00:24:27,800
more propensity for anxiety. 
And when I look back and look at

443
00:24:27,800 --> 00:24:30,800
that stuff that was going on my 
early twenties with the nervous 

444
00:24:30,800 --> 00:24:34,300
system, dysfunction. 
I That I was actually set up in 

445
00:24:34,300 --> 00:24:38,900
some ways from an epigenetic, 
expect perspective to respond, 

446
00:24:39,200 --> 00:24:42,900
abnormally to like minor 
stressors in this kind of really

447
00:24:42,900 --> 00:24:46,400
exaggerated kind of way. 
So so my path has been a lot of 

448
00:24:46,400 --> 00:24:49,000
meditation. 
A lot of breathing techniques, a

449
00:24:49,008 --> 00:24:53,400
lot of things that really work 
to epigenetic alter some of 

450
00:24:53,400 --> 00:24:56,700
those stress related genes. 
Well, it's crazy because like 

451
00:24:56,700 --> 00:24:59,000
you start looking at just to 
current day and age, you know, 

452
00:24:59,000 --> 00:25:01,900
like with what we have going the
world with the virus right now 

453
00:25:02,000 --> 00:25:05,600
and Everybody is like like just 
you know shutting themselves and

454
00:25:05,600 --> 00:25:08,200
their house and basically living
in a bubble. 

455
00:25:08,300 --> 00:25:12,800
I mean I don't think it's too 
much too kind of anticipate that

456
00:25:12,800 --> 00:25:15,800
that's going to have an 
epigenetic effect on possibly 

457
00:25:15,800 --> 00:25:17,200
future Generations immune 
system. 

458
00:25:17,200 --> 00:25:19,800
Like if you're just stuck in a 
bubble and not going out and 

459
00:25:19,800 --> 00:25:21,900
always wearing a mask and you're
not being exposed to just 

460
00:25:21,900 --> 00:25:25,500
day-to-day normal bacteria that 
you would probably build up an 

461
00:25:25,500 --> 00:25:28,500
epigenetic. 
No tolerance for maybe a totally

462
00:25:28,500 --> 00:25:30,800
off the off the wall, but it 
makes sense to me. 

463
00:25:31,600 --> 00:25:35,100
Yeah, you know, I Think that I'm
personally more concerned about 

464
00:25:35,100 --> 00:25:38,500
the stress effects, you know, I 
think people even if they're 

465
00:25:38,500 --> 00:25:41,300
wearing a mask and they're in, 
you know, more inside, I think 

466
00:25:41,300 --> 00:25:45,700
there's still getting some 
degree of bacterial transfer. 

467
00:25:46,100 --> 00:25:48,400
But I would be more way more 
concerned about the effects of 

468
00:25:48,400 --> 00:25:51,100
stress at this point on future 
Generations. 

469
00:25:51,100 --> 00:25:53,900
Just in terms of the financial 
and security of the people are 

470
00:25:53,900 --> 00:25:57,100
experiencing. 
I mean, we've seen, you know, 

471
00:25:57,100 --> 00:26:00,300
suicide levels domestic 
violence, all these things Spike

472
00:26:00,700 --> 00:26:06,900
and there's Just robust data 
that stress, both during 

473
00:26:06,900 --> 00:26:09,200
preconception, like before you 
even get pregnant. 

474
00:26:09,200 --> 00:26:12,500
That like the three-month period
is a critical window of what's 

475
00:26:12,500 --> 00:26:14,300
going on before you get 
pregnant. 

476
00:26:14,400 --> 00:26:19,000
What what's programming, sperm? 
And egg selection as well as 

477
00:26:19,000 --> 00:26:22,900
during pregnancy? 
I mean, chronic stress is really

478
00:26:22,900 --> 00:26:27,200
detrimental to Future 
Generations like that. 

479
00:26:27,200 --> 00:26:31,600
So I mean I yeah I'm concerned I
and and incidentally that will 

480
00:26:31,600 --> 00:26:34,300
probably also Actually immune 
system as well. 

481
00:26:35,300 --> 00:26:40,300
I would attribute it more to the
stress response and, you know, 

482
00:26:40,308 --> 00:26:41,400
you kind of want to think about 
it. 

483
00:26:41,400 --> 00:26:49,100
Like, when our bodies are 
conceiving, we're trying to 

484
00:26:49,100 --> 00:26:52,600
select egg and sperm in a way 
that prepares the future 

485
00:26:52,600 --> 00:26:56,900
generation to be able to respond
to what the current environment 

486
00:26:56,900 --> 00:27:00,100
is right now, for the parents. 
So if we're in a high-stress 

487
00:27:00,100 --> 00:27:02,300
environment, we're going to try 
and set up. 

488
00:27:02,400 --> 00:27:05,600
Up our kids to have this 
heightened stress response, 

489
00:27:05,900 --> 00:27:08,500
that, you know, is adaptive, 
right? 

490
00:27:08,500 --> 00:27:10,400
None of these things are 
pathological. 

491
00:27:10,400 --> 00:27:15,900
They're all just adaptations and
unfortunately when we're putting

492
00:27:15,900 --> 00:27:20,500
ourselves in an environment that
looks like an adaptation that 

493
00:27:20,500 --> 00:27:23,800
creates more anxiety or 
depression as a way to respond 

494
00:27:23,800 --> 00:27:25,400
to this. 
It's like, you know, that's what

495
00:27:25,400 --> 00:27:28,400
we're seeing right now. 
And yeah, I'm pretty concerned 

496
00:27:28,400 --> 00:27:31,100
about that as well. 
This would be an impossible 

497
00:27:31,100 --> 00:27:33,600
question to answer and Except 
I'm not even fair question to 

498
00:27:33,608 --> 00:27:37,300
ask, but I'm just curious, but 
with what you're seeing and what

499
00:27:37,300 --> 00:27:40,600
you know about genetics 
epigenetics and kind of how our 

500
00:27:40,600 --> 00:27:43,600
lifestyle factors and 
environmental factors impact, 

501
00:27:43,600 --> 00:27:46,100
this egg and sperm selection and
just, you know, future 

502
00:27:46,100 --> 00:27:50,000
Generations. 
Do you feel like just our 

503
00:27:50,000 --> 00:27:52,100
population as a whole? 
I mean, you look at what people 

504
00:27:52,100 --> 00:27:55,400
are consuming from a nutritional
standpoint, how their living 

505
00:27:55,400 --> 00:27:57,100
from a lifestyle standpoint. 
I mean, they're definitely 

506
00:27:57,100 --> 00:28:01,500
outliers for sure. 
But, do you feel like we're 

507
00:28:01,500 --> 00:28:03,800
headed in the right direction? 
Trajectory the wrong trajectory 

508
00:28:03,800 --> 00:28:08,200
without me to Doom and Gloom. 
Here I would say on average 

509
00:28:08,200 --> 00:28:14,300
probably the wrong trajectory. 
But again, I have faith in the 

510
00:28:14,300 --> 00:28:18,500
outliers, I have, I have General
Faith, you know, I'm an optimist

511
00:28:18,500 --> 00:28:22,200
overall. 
I think that people are aware. 

512
00:28:22,200 --> 00:28:25,900
There's something wrong here. 
There are people are aware that 

513
00:28:26,000 --> 00:28:29,000
food. 
They're eating isn't real food, 

514
00:28:29,000 --> 00:28:36,100
you know, and I like to work 
with the outliers that are aware

515
00:28:36,300 --> 00:28:40,600
of this stuff in hopes, that 
that understanding will spread. 

516
00:28:40,900 --> 00:28:48,500
And I'm totally not an expert on
policy or ways to shift this in 

517
00:28:48,500 --> 00:28:54,200
a mass level. 
But I do sense that there's a 

518
00:28:55,500 --> 00:29:04,100
Bit of a kind of shift in the 
general desire to have a better 

519
00:29:04,100 --> 00:29:08,700
healthier lifestyle overall. 
And think people generally 

520
00:29:08,700 --> 00:29:12,000
recognized that like, pumping 
ourselves Pharmaceuticals, and, 

521
00:29:12,500 --> 00:29:15,900
and Fruit Loops, like just isn't
a health-promoting thing. 

522
00:29:15,900 --> 00:29:19,100
Now, the behavior change aspect 
and getting out of the habit of 

523
00:29:19,100 --> 00:29:21,700
that, that's a totally different
conversation. 

524
00:29:21,700 --> 00:29:24,100
I think a lot of more people 
want to do that. 

525
00:29:24,100 --> 00:29:26,400
Then are able To right now, you 
know? 

526
00:29:26,600 --> 00:29:29,500
Yeah, that makes sense. 
And I don't want to be so stuck 

527
00:29:29,500 --> 00:29:33,200
in my echo chamber of like the 
biohacking, ketogenic, low-carb,

528
00:29:33,200 --> 00:29:37,300
space that I don't, you know, 
see, things holistically, I 

529
00:29:37,300 --> 00:29:39,600
mean, because it just seems like
everybody that I'm interacting 

530
00:29:39,600 --> 00:29:42,100
with the communicating, with, on
a regular basis, they're all 

531
00:29:42,100 --> 00:29:45,600
relatively educated in the know 
about epigenetics and kind of 

532
00:29:45,600 --> 00:29:49,400
the compounding effect that has.
So I'm always curious to get an 

533
00:29:49,400 --> 00:29:52,600
outside perspective on what the 
overall pulse of the community 

534
00:29:52,600 --> 00:29:55,000
is. 
So it's super interesting for 

535
00:29:55,000 --> 00:29:55,400
sure. 
Sure. 

536
00:29:55,400 --> 00:29:57,700
But yeah, we got we got to be 
optimistic again. 

537
00:29:57,700 --> 00:30:00,700
No, good in being pessimistic 
with it, but realistic the same 

538
00:30:00,700 --> 00:30:03,700
time. 
Yeah, realistic and you know, 

539
00:30:03,700 --> 00:30:07,100
again it's there's the the 
complex interaction between 

540
00:30:07,100 --> 00:30:12,200
personal choice and desire and 
then say economic status and 

541
00:30:12,200 --> 00:30:17,800
what the broader kind of 
abilities of people are to say 

542
00:30:18,600 --> 00:30:21,700
get information and you know you
some people don't even have 

543
00:30:21,700 --> 00:30:24,600
internet access, you know, it's 
kind of that. 

544
00:30:25,400 --> 00:30:29,500
Um, it is easy to get stuck in 
her own bubbles of like of 

545
00:30:29,500 --> 00:30:32,700
like-minded, people who really 
are passionate about this stuff.

546
00:30:33,300 --> 00:30:39,700
I would love to see the 
mentality of just Wellness in 

547
00:30:39,700 --> 00:30:46,700
general, be a more broadly 
adopted and I mentality and the 

548
00:30:46,700 --> 00:30:49,500
general public, you know, I 
think every everyone benefits 

549
00:30:49,500 --> 00:30:53,200
from that right hundred percent,
you had mentioned like breathing

550
00:30:53,200 --> 00:30:56,500
techniques for stress reduction.
You kind of dive in a little bit

551
00:30:56,500 --> 00:30:58,100
further. 
Oh yeah, sure. 

552
00:30:59,500 --> 00:31:02,100
So where do you want to start? 
I could talk about some 

553
00:31:02,100 --> 00:31:03,900
different different aspects of 
it. 

554
00:31:04,100 --> 00:31:04,600
Yeah. 
Yeah. 

555
00:31:04,600 --> 00:31:06,500
I mean just kind of like make it
applicable. 

556
00:31:06,500 --> 00:31:09,900
I mean I'm always stressful 
knowing some good, go to 

557
00:31:09,900 --> 00:31:12,700
brilliant techniques. 
Probably beneficial sure. 

558
00:31:12,700 --> 00:31:17,300
So there's two that I really 
like that. 

559
00:31:17,300 --> 00:31:19,100
I teach to two clients kind of 
right away. 

560
00:31:19,100 --> 00:31:24,800
The first one is what I call 
this belly breathing and this is

561
00:31:24,800 --> 00:31:28,300
really Are you breathing, low, 
and slow? 

562
00:31:28,300 --> 00:31:33,500
And by low, I mean, you're 
actually instead of centering 

563
00:31:33,500 --> 00:31:36,900
your, your breath, into your 
chest, which is how most people 

564
00:31:36,900 --> 00:31:39,800
breathe, you're really pushing 
it down into your diaphragm. 

565
00:31:40,200 --> 00:31:45,100
And the reason for this is that 
there's a nerve in the body 

566
00:31:45,100 --> 00:31:50,500
called the vagus nerve that 
connects the brain to all of the

567
00:31:50,500 --> 00:31:55,100
other organs in the body. 
And it also is responsible for 

568
00:31:55,300 --> 00:31:59,300
The branches of the nervous 
system and controlling our fight

569
00:31:59,300 --> 00:32:02,100
or flight response and a 
relaxation response. 

570
00:32:02,500 --> 00:32:06,800
And there's actually a ton of 
these nerve endings in the 

571
00:32:06,808 --> 00:32:09,900
diaphragm area in the stomach 
because it connects to all these

572
00:32:09,900 --> 00:32:13,100
organs. 
And so when you physically 

573
00:32:13,100 --> 00:32:18,300
extend and distend your stomach 
in your diaphragm and that way, 

574
00:32:18,300 --> 00:32:22,200
you're actually stimulating the 
vagus nerve and that can help 

575
00:32:22,600 --> 00:32:28,800
physically calm your body down. 
And trying to do this at a rate 

576
00:32:28,800 --> 00:32:31,700
of about five or six seconds on 
the in-breath five or six 

577
00:32:31,700 --> 00:32:35,400
seconds on the out-breath has 
been found to be kind of the 

578
00:32:35,400 --> 00:32:37,600
optimal breathing rate for doing
this. 

579
00:32:38,500 --> 00:32:42,000
So you know, an easy way to do 
it is you put one hand on your 

580
00:32:42,000 --> 00:32:45,000
chest, kind of right over your 
heart and one hand. 

581
00:32:45,000 --> 00:32:47,700
Right over your stomach, over 
your belly button, and you just 

582
00:32:47,700 --> 00:32:53,400
feel where your breath is, 
moving your body and slowly, you

583
00:32:53,400 --> 00:32:55,100
just try and move the bottom 
hand. 

584
00:32:55,200 --> 00:32:58,900
And more with each in breath and
out breath, and kind of shift 

585
00:32:58,900 --> 00:33:02,300
that Focus from the chest 
breathing down to the belly 

586
00:33:02,300 --> 00:33:04,700
breathing. 
And this is a good exercise to 

587
00:33:04,700 --> 00:33:07,100
do. 
You know, just three to five 

588
00:33:07,100 --> 00:33:08,900
minutes can make a pretty big 
difference. 

589
00:33:09,300 --> 00:33:15,100
And this is also something that 
can be helpful for improving 

590
00:33:15,100 --> 00:33:19,300
actually recovery. 
From exercise, the vagus nerve 

591
00:33:19,300 --> 00:33:22,000
and that parasympathetic 
sympathetic nervous system 

592
00:33:22,000 --> 00:33:25,200
response is really important in 
terms. 

593
00:33:25,300 --> 00:33:29,300
Of heart rate variability. 
And, you know, it's a 

594
00:33:29,308 --> 00:33:33,200
measurement that a lot of people
will use to gauge Readiness for 

595
00:33:33,400 --> 00:33:35,300
extreme training that type of 
thing. 

596
00:33:35,300 --> 00:33:38,400
And look at how that changes and
how people recover. 

597
00:33:38,700 --> 00:33:42,100
So optimizing kind of the vagus 
nerve optimizing. 

598
00:33:42,100 --> 00:33:44,800
The branches of the nervous 
system can actually help your 

599
00:33:44,800 --> 00:33:47,700
body recover from from heavy 
exercises as well better. 

600
00:33:48,200 --> 00:33:53,400
And in general, I mean it it is 
going to improve mood. 

601
00:33:53,400 --> 00:33:58,100
Improved stress, response, 
improve, Oof anxiety, and mental

602
00:33:58,100 --> 00:34:00,600
looping, that type of thing, and
it's a good thing. 

603
00:34:00,600 --> 00:34:04,800
Just to practice for 5-10 
minutes a day, if you can, I've 

604
00:34:04,800 --> 00:34:07,000
been trying to do stuff like 
this, like the, the breathing 

605
00:34:07,000 --> 00:34:10,900
techniques prior to consuming a 
meal, because I used to just 

606
00:34:10,900 --> 00:34:13,100
like scarf down a Maryland and 
not think twice about it. 

607
00:34:13,100 --> 00:34:15,400
But then I got to thinking, you 
know, your if your body is in a 

608
00:34:15,400 --> 00:34:18,500
sympathetic State, you're not 
really absorbing all of those 

609
00:34:18,500 --> 00:34:20,800
macronutrients. 
So you can be consuming, you 

610
00:34:20,800 --> 00:34:24,800
know, a very specific, you know,
counted out number of protein 

611
00:34:24,800 --> 00:34:27,300
fat and Hundreds, whatever. 
But if you're not absorbing it, 

612
00:34:27,300 --> 00:34:29,800
what's the point? 
So kind of focusing on my 

613
00:34:29,800 --> 00:34:32,300
breathing in reaching a 
parasympathetic State before 

614
00:34:32,300 --> 00:34:35,000
food consumption. 
I feel like that makes it pretty

615
00:34:35,000 --> 00:34:37,000
tangible difference. 
Yeah. 

616
00:34:37,000 --> 00:34:40,100
Absolutely. 
That's actually in a person. 

617
00:34:41,800 --> 00:34:44,900
Oh exploration of my to recently
are really trying to track that 

618
00:34:44,900 --> 00:34:48,800
and see how my body responds. 
And yeah, I think that's 

619
00:34:48,800 --> 00:34:51,199
critical like, sometimes it's 
how you eat is just as important

620
00:34:51,199 --> 00:34:54,300
as what you eat, I noticed, 
like, I would do this, you know,

621
00:34:54,300 --> 00:34:57,400
in my contest prep one, my 
calories were very low, and I 

622
00:34:57,408 --> 00:35:01,700
would notice that my satiety 
would actually be noticeably 

623
00:35:01,700 --> 00:35:04,600
better on days where I would 
focus on breathing prior to that

624
00:35:04,600 --> 00:35:07,500
meal because it's like, my body 
was actually absorbing the 

625
00:35:07,500 --> 00:35:10,800
nutrients rather than just being
flushed through my system. 

626
00:35:11,000 --> 00:35:12,500
And because I Better nutrient 
absorption. 

627
00:35:12,500 --> 00:35:13,900
I had more steady throughout the
day. 

628
00:35:14,500 --> 00:35:15,800
Totally. 
And it's like, if you think 

629
00:35:15,800 --> 00:35:20,200
about it, you know, how is your 
body going to respond to eating 

630
00:35:20,200 --> 00:35:21,900
while you're running from the 
tiger vs. 

631
00:35:21,900 --> 00:35:25,200
Eating while you're sitting 
kicking back and enjoying life? 

632
00:35:25,200 --> 00:35:28,100
Like that's, there's going to be
some different hormones secreted

633
00:35:28,100 --> 00:35:30,700
in those different situations. 
Definitely, definitely. 

634
00:35:31,100 --> 00:35:33,000
What was the other brilliant? 
You said there's two that you 

635
00:35:33,000 --> 00:35:34,800
typically go to from the get-go?
Yeah, yeah. 

636
00:35:34,800 --> 00:35:36,300
The other one is called box 
breathing. 

637
00:35:36,400 --> 00:35:42,500
And this comes actually from 
military from From seal special 

638
00:35:42,500 --> 00:35:48,600
training that type of world and 
the, the pattern is breathe in. 

639
00:35:48,600 --> 00:35:51,700
For four counts. 
You hold that for four counts 

640
00:35:52,100 --> 00:35:54,600
and you breathe out for four 
counts and you hold that for 

641
00:35:54,600 --> 00:35:56,800
four counts. 
So you can imagine it's like a 

642
00:35:56,800 --> 00:36:01,400
box with four equal sides and 
it's a really good focusing 

643
00:36:01,400 --> 00:36:06,100
breath. 
It's it's like more of a in a 

644
00:36:06,100 --> 00:36:10,400
tactical situation I need to 
call my body down really quick. 

645
00:36:10,400 --> 00:36:14,400
I need to be able to Locusts and
know what my surroundings are 

646
00:36:14,700 --> 00:36:18,000
and just put my body in a state 
where I'm in flow. 

647
00:36:18,100 --> 00:36:21,000
So it's a really good flow. 
Kind of breaths a little bit 

648
00:36:21,000 --> 00:36:26,900
more of an active thing than the
belly breathing and the the 

649
00:36:26,900 --> 00:36:30,500
pausing in between the in-breath
and the out-breath is really the

650
00:36:30,500 --> 00:36:33,800
key with it. 
So it's just four counts based 

651
00:36:33,800 --> 00:36:37,200
on each side of that box in out 
in out and just repeat. 

652
00:36:38,000 --> 00:36:42,500
Yep. 
Nice in hold out, hold Gotcha. 

653
00:36:42,700 --> 00:36:45,800
Gotcha. 
You would also mention come 

654
00:36:45,800 --> 00:36:48,800
before I started recording, how 
you taken a keen interest 

655
00:36:48,800 --> 00:36:52,800
towards the genetic. 
Predisposition of someone and 

656
00:36:52,800 --> 00:36:56,300
their body's ability to benefit 
or not benefit. 

657
00:36:56,300 --> 00:36:59,800
I guess from certain 
cannabinoids and all that this 

658
00:36:59,800 --> 00:37:02,300
is unchartered territory for me,
for sure. 

659
00:37:02,300 --> 00:37:05,100
So I'd love to kind of just dive
into that because there's a lot 

660
00:37:05,100 --> 00:37:08,800
of interest around, you know, 
CBD THC has become legalized in 

661
00:37:08,800 --> 00:37:10,900
a lot of states. 
And again, this is not my area 

662
00:37:10,900 --> 00:37:14,300
of He's managed imagination. 
So shed some light on that for 

663
00:37:14,300 --> 00:37:16,200
me. 
Yeah, absolutely. 

664
00:37:16,200 --> 00:37:19,500
Well, you know, even if it's not
your area of expertise, I'm sure

665
00:37:19,500 --> 00:37:22,300
you've noticed that some people 
are just naturally attracted to 

666
00:37:22,300 --> 00:37:24,700
cannabis. 
And some people really could 

667
00:37:24,700 --> 00:37:26,900
care less, or really don't like 
it. 

668
00:37:27,300 --> 00:37:33,900
And there are some pretty strong
genetic correlations with these 

669
00:37:33,900 --> 00:37:37,300
Dynamics, in the way, people 
respond to cannabinoids and I 

670
00:37:37,300 --> 00:37:41,100
got really interested in this a 
couple years ago when I was 

671
00:37:41,100 --> 00:37:44,300
getting Ting first getting into 
the Nutri genetics with 

672
00:37:44,300 --> 00:37:47,600
nutrition and what we're just 
talking about and realize 

673
00:37:47,600 --> 00:37:53,200
there's actually quite a few 
good studies on the same gene 

674
00:37:53,200 --> 00:37:56,700
variations and response cannabis
and there just wasn't a lot of 

675
00:37:56,707 --> 00:37:59,600
people talking about it. 
So I've actually over the past 

676
00:37:59,600 --> 00:38:04,300
couple years developed a test 
that looks at response to 

677
00:38:04,300 --> 00:38:07,500
cannabinoids and some of the 
things that you can really 

678
00:38:07,600 --> 00:38:11,300
predict well are things like how
you metabolize and breakdown. 

679
00:38:11,500 --> 00:38:13,400
HC. 
Are you someone that's going to 

680
00:38:13,400 --> 00:38:16,200
be very sensitive to it or 
someone who can probably take 

681
00:38:16,200 --> 00:38:21,300
higher doses of it and be okay? 
Things that influence cognitive 

682
00:38:21,300 --> 00:38:26,500
function, you know, there's kind
of the the stereotypical notion 

683
00:38:26,500 --> 00:38:30,000
of like the stoner who can't get
off the couch and can't remember

684
00:38:30,000 --> 00:38:34,400
anything nurses, say someone 
like Snoop Dogg who has you know

685
00:38:34,400 --> 00:38:36,800
built an Empire while smoking 
blunts. 

686
00:38:37,100 --> 00:38:42,000
So clearly there's some type of 
different In difference in 

687
00:38:42,000 --> 00:38:45,400
Constitution. 
And so a lot of the studies that

688
00:38:45,400 --> 00:38:49,000
have been done are actually on 
cognitive function and response 

689
00:38:49,000 --> 00:38:52,400
to th see when people use it. 
And, you know, doing things like

690
00:38:52,800 --> 00:38:56,000
consuming THC and then giving 
people memory tests or looking 

691
00:38:56,000 --> 00:39:02,300
at reaction time and various 
domains and you can get a feel 

692
00:39:02,300 --> 00:39:03,800
for. 
Are you some of that's going to 

693
00:39:03,800 --> 00:39:07,900
be more or less functional with 
this and art and ways to change 

694
00:39:08,000 --> 00:39:10,900
supplements or other herbs or 
different? 

695
00:39:11,100 --> 00:39:13,400
Trains to kind of interact with 
that. 

696
00:39:13,800 --> 00:39:16,700
And furthermore, one of the 
other strength is actually 

697
00:39:16,700 --> 00:39:20,500
predicting negative responses 
from th see, you know I'm 

698
00:39:20,500 --> 00:39:24,700
generally Pro cognitive Liberty,
like the idea that people should

699
00:39:24,700 --> 00:39:27,700
be able to put whatever they 
want in their bodies and change 

700
00:39:27,700 --> 00:39:32,200
their Consciousness and whatever
way is you know they choose as 

701
00:39:32,200 --> 00:39:35,700
long as it's not harming other 
people, but at the same time, 

702
00:39:35,700 --> 00:39:38,200
you know, being relatively 
pro-legalization, I think it's 

703
00:39:38,200 --> 00:39:40,900
equally important to talk about 
the potential risks. 

704
00:39:41,300 --> 00:39:46,000
And for certain people THC, use 
does increase the risk of 

705
00:39:46,000 --> 00:39:50,300
psychosis or schizophrenia, and 
there's some genetics that it 

706
00:39:50,300 --> 00:39:54,300
can be informative around that. 
In terms of looking at, hey, 

707
00:39:54,300 --> 00:39:58,000
does this pose more of a risk 
for U-verse other people, 

708
00:39:58,700 --> 00:40:00,700
especially in the context of a 
younger? 

709
00:40:01,100 --> 00:40:03,300
You know, not fully developed 
individual front. 

710
00:40:03,600 --> 00:40:04,500
Right? 
Exactly. 

711
00:40:04,500 --> 00:40:08,200
And you know, most, I would say 
that for the majority of people 

712
00:40:08,200 --> 00:40:09,700
that are younger, it's probably 
a good idea. 

713
00:40:09,700 --> 00:40:12,200
Not to use th see each other. 
It is more developed. 

714
00:40:12,300 --> 00:40:15,100
I certainly didn't follow that 
when I was younger and I wished 

715
00:40:15,100 --> 00:40:20,200
I had, I wish I had now, but 
yeah I can definitely give you a

716
00:40:20,200 --> 00:40:23,300
better indication of you know, 
are there other risk factors 

717
00:40:23,300 --> 00:40:26,500
with it for most people know? 
But for certain people it's 

718
00:40:26,500 --> 00:40:30,600
worth having that conversation. 
I think as real as a responsible

719
00:40:31,400 --> 00:40:35,400
Pro cannabis person, got ya I 
got ya. 

720
00:40:35,400 --> 00:40:38,800
This this is it's interesting to
me because there's always like 

721
00:40:38,800 --> 00:40:42,500
this, you know, shade of gray. 
Ray and people always want to 

722
00:40:42,500 --> 00:40:45,200
compartmentalize and put in, you
know, black and white. 

723
00:40:46,300 --> 00:40:50,300
But I said I don't really know 
much about near the legalization

724
00:40:50,300 --> 00:40:52,600
to politics, anything like that.
But I've been like really just 

725
00:40:52,600 --> 00:40:55,200
diving into what people are 
saying and kind of where they're

726
00:40:55,200 --> 00:40:58,000
coming from, what they've got, 
like an educated responsible 

727
00:40:58,000 --> 00:41:02,100
reason for what they're 
advocating for and the more the 

728
00:41:02,100 --> 00:41:04,900
deeper, I dive, it becomes just 
more and more apparent that it's

729
00:41:04,900 --> 00:41:08,700
so individualized. 
And now that we're seeing how 

730
00:41:08,800 --> 00:41:12,100
the genetics can have such a, 
you know, Impact on how they're 

731
00:41:12,100 --> 00:41:13,300
going to respond. 
That makes sense. 

732
00:41:13,300 --> 00:41:14,700
That would be very 
individualized. 

733
00:41:15,600 --> 00:41:17,900
Yeah. 
And, you know, one thing that's 

734
00:41:17,900 --> 00:41:22,800
kind of important to know is you
see CBD is being touted for 

735
00:41:22,800 --> 00:41:24,500
being good for so many different
things. 

736
00:41:24,500 --> 00:41:29,400
It's like if it's a condition, 
it works for someone for it, you

737
00:41:29,400 --> 00:41:30,700
know, it can help you win the 
lottery. 

738
00:41:30,700 --> 00:41:36,000
It can do everything but and you
know, that confuses a lot of 

739
00:41:36,000 --> 00:41:39,500
people. 
But the one thing that is really

740
00:41:39,500 --> 00:41:41,600
critical is that the 
endocannabinoids Annoyed system 

741
00:41:41,600 --> 00:41:46,000
itself, The receptors that are 
scattered throughout the body 

742
00:41:46,000 --> 00:41:49,000
are present on essentially every
single cell type. 

743
00:41:49,100 --> 00:41:53,200
So every system of the body has 
a back door through the 

744
00:41:53,200 --> 00:41:56,600
endocannabinoid system, which is
why you see it so effective for 

745
00:41:56,600 --> 00:42:03,200
so many things, the nervous 
system, you know, the pulmonary 

746
00:42:03,200 --> 00:42:07,200
system, every system in the body
has a relationship to the 

747
00:42:07,200 --> 00:42:10,900
endocannabinoid system. 
So for certain people if that's 

748
00:42:11,100 --> 00:42:16,600
Imbalanced adding CBD or in some
cases to uh see might be the 

749
00:42:16,600 --> 00:42:19,100
solution for those. 
Those people if they're not 

750
00:42:19,100 --> 00:42:22,500
getting success from other 
routes, that are not really 

751
00:42:22,500 --> 00:42:25,500
looking at that that layer that 
sits underneath these other 

752
00:42:25,500 --> 00:42:29,200
systems. 
So it's it's incredibly 

753
00:42:29,200 --> 00:42:33,000
individual and there's something
that's known as the 

754
00:42:33,000 --> 00:42:36,700
endocannabinoids high deficiency
hypothesis that, you know, I 

755
00:42:36,700 --> 00:42:39,900
think is worth mentioning and in
that some people are prone 

756
00:42:39,900 --> 00:42:43,300
naturally to have Higher lower 
levels of their own cannabinoids

757
00:42:43,300 --> 00:42:45,500
that the body makes you know 
with usually think about 

758
00:42:45,500 --> 00:42:49,500
cannabinoids as things from 
plants or synthetic things. 

759
00:42:49,500 --> 00:42:52,900
But our body also produces our 
own, which is why we have these 

760
00:42:52,900 --> 00:42:55,700
robust receptor systems all 
throughout the body. 

761
00:42:56,100 --> 00:43:02,000
And there's certain traits that 
go with either deficient 

762
00:43:02,000 --> 00:43:06,300
cannabinoids or excess like 
obesity is actually associated 

763
00:43:06,300 --> 00:43:10,200
with having high levels of your 
own endocannabinoids on the flip

764
00:43:10,200 --> 00:43:13,200
side. 
I'm like anxiety is associated 

765
00:43:13,200 --> 00:43:17,400
with low levels and so depending
on, you know what, the person's 

766
00:43:17,400 --> 00:43:20,100
health status is and what goals 
they have. 

767
00:43:20,400 --> 00:43:23,400
You might look at different 
cannabinoids for those things 

768
00:43:23,700 --> 00:43:27,100
and looking at the genetics can 
also give you an understanding 

769
00:43:27,100 --> 00:43:30,400
of, you know, are you more or 
less likely to carry higher or 

770
00:43:30,400 --> 00:43:34,100
lower levels of cannabinoids? 
So that's another genetic factor

771
00:43:34,100 --> 00:43:38,700
that some people can be more 
predisposed to and this inner 

772
00:43:38,700 --> 00:43:40,700
cannabinoid system. 
Emits, I've heard it referred to

773
00:43:40,700 --> 00:43:44,400
as Like the, you get the, the, 
your brain obviously, and you've

774
00:43:44,400 --> 00:43:47,500
got your gut, which is often 
times referred to as the second 

775
00:43:47,500 --> 00:43:49,100
brain. 
And then this inner cannabinoid 

776
00:43:49,100 --> 00:43:51,800
system is, I've heard it 
referred to as like the third 

777
00:43:51,800 --> 00:43:55,900
brain, almost I would say that's
pretty accurate. 

778
00:43:55,900 --> 00:44:00,000
One of the things that it does 
and it is, is it can balance 

779
00:44:00,000 --> 00:44:05,500
neurotransmission in a way that 
if you have neurons that are 

780
00:44:05,500 --> 00:44:08,000
say, under firing it can 
actually speed up the 

781
00:44:08,000 --> 00:44:12,300
transmission cause them to kind 
of it's almost like an adaptogen

782
00:44:13,000 --> 00:44:17,900
and endocannabinoids can also 
inhibit over transmission of 

783
00:44:17,900 --> 00:44:22,500
neurons so it does act as this 
balancing agent in that kind of 

784
00:44:22,500 --> 00:44:25,000
way. 
So like like marijuana for 

785
00:44:25,000 --> 00:44:28,300
instance, that has gaetz, you 
know, the full spectrum. 

786
00:44:28,300 --> 00:44:30,700
So it's got all like how many 
different cannabinoids are 

787
00:44:30,700 --> 00:44:33,400
there. 
There is actually over 100. 

788
00:44:33,400 --> 00:44:38,800
We know right now about maybe 
what, eight, to ten of them do 

789
00:44:38,800 --> 00:44:43,500
pretty well. 
And of those eight THC, and CBD 

790
00:44:43,500 --> 00:44:47,000
are really the only ones that 
have had significant clinical 

791
00:44:47,000 --> 00:44:50,100
trials on them. 
So this is why a lot of people 

792
00:44:50,100 --> 00:44:52,800
are so excited about it is 
because it's kind of a wild wild

793
00:44:52,800 --> 00:44:55,400
west. 
Stand wide open for future, 

794
00:44:55,400 --> 00:44:57,500
exploration. 
And we are understanding of it 

795
00:44:57,500 --> 00:45:00,200
is very, very small right now. 
Catch it. 

796
00:45:00,200 --> 00:45:01,300
Catch it makes sense. 
Yeah. 

797
00:45:01,300 --> 00:45:05,300
I feel like, you know, CBDs have
gotten just this massive amount 

798
00:45:05,300 --> 00:45:08,000
of hype, but I feel like some of
the marketing is ahead of some 

799
00:45:08,000 --> 00:45:10,300
of the science guys. 
Like you see this this 

800
00:45:10,300 --> 00:45:14,600
marketing, you know, freight 
train coming everywhere, but I 

801
00:45:14,600 --> 00:45:18,300
am curious to dive deeper into 
this and see, you know, from a 

802
00:45:18,300 --> 00:45:21,400
genetic standpoint but also from
like a, you know, if someone's 

803
00:45:21,400 --> 00:45:24,400
got a deficiency, could this? 
This, you know, benefit them in 

804
00:45:24,400 --> 00:45:26,300
some form of fashion, get 
something firing more 

805
00:45:26,300 --> 00:45:29,000
effectively. 
It's interesting to make it, you

806
00:45:29,000 --> 00:45:31,700
know, all full circle and see 
how, you know, how your 

807
00:45:31,700 --> 00:45:33,700
environmental factors, what your
trainings like what your 

808
00:45:33,700 --> 00:45:36,900
nutrition is like and then this 
no third, brain inner 

809
00:45:36,900 --> 00:45:39,900
cannabinoid system, how that can
be also leverage to reach a 

810
00:45:39,900 --> 00:45:43,000
specific goal, right? 
And I love the way you phrase 

811
00:45:43,000 --> 00:45:46,600
that, I mean, I look at 
cannabinoids as just another 

812
00:45:46,600 --> 00:45:49,800
piece of the whole system's 
puzzle, right? 

813
00:45:49,800 --> 00:45:52,800
It's, you know, I think that's 
part of the the marketing hype. 

814
00:45:53,000 --> 00:45:58,600
That frustrates me is the idea 
that a will, you just need to 

815
00:45:58,600 --> 00:46:02,100
use CBD and you know, the then 
that's that's it, right? 

816
00:46:02,100 --> 00:46:04,800
It's now, it's part of the 
regimen, it's part of the 

817
00:46:04,800 --> 00:46:07,100
routine. 
And for some people, it can be 

818
00:46:08,000 --> 00:46:11,900
profoundly helpful, especially 
for things like, you know, 

819
00:46:11,900 --> 00:46:14,300
anything, that's inflammation, 
related, it is very worth 

820
00:46:14,300 --> 00:46:20,600
trying, and one of the actions 
of CBD that I think is often, 

821
00:46:20,600 --> 00:46:26,200
overlooked is CBD doesn't 
directly activate cannabinoid 

822
00:46:26,200 --> 00:46:33,600
receptors really very very weak.
Interaction THC is a, you know, 

823
00:46:33,600 --> 00:46:36,700
powerful Agonist at receptor so 
it directly activates them. 

824
00:46:37,100 --> 00:46:41,800
One of the things that CBD does 
really well is it inhibits the 

825
00:46:41,800 --> 00:46:45,000
enzymes that break down some of 
our own cannabinoids. 

826
00:46:45,200 --> 00:46:49,000
So it raises the levels of our 
cannabinoids, the ones that are 

827
00:46:49,000 --> 00:46:51,500
in our body that, you know, that
are in psychoactive that just 

828
00:46:51,500 --> 00:46:57,100
act as these regulatory. 
Actors and so CBD gives our 

829
00:46:57,100 --> 00:47:01,000
body, you know, if we are out of
balance and we are not producing

830
00:47:01,000 --> 00:47:02,800
enough of our own 
endocannabinoids for whatever 

831
00:47:02,800 --> 00:47:08,400
reason, CBD kind of corrects 
that balance at the level of 

832
00:47:08,400 --> 00:47:11,800
allowing our body to kind of 
produce the, the biochemicals 

833
00:47:11,800 --> 00:47:16,000
that it's used to rather than, 
you know, something like THC, 

834
00:47:16,000 --> 00:47:18,800
which again, can be really 
useful, but it's a little bit 

835
00:47:18,800 --> 00:47:25,300
more of a, how do I put this? 
Kind of shock to the system in a

836
00:47:25,300 --> 00:47:29,700
way, you know, there's a little 
bit more of a of a downstream 

837
00:47:29,700 --> 00:47:35,100
effect potential for THC, where 
the CBD is very gentle and its 

838
00:47:35,100 --> 00:47:39,100
action in terms of how it just 
gets your body to have more of a

839
00:47:39,700 --> 00:47:41,100
substance. 
It's producing naturally. 

840
00:47:41,100 --> 00:47:45,500
Anyway, now in regards to cvd, 
is it better? 

841
00:47:45,800 --> 00:47:49,500
Or is it in different to have 
like a CBD isolate or one? 

842
00:47:49,500 --> 00:47:53,500
That's like a full spectrum CBD 
that has, you know, Amounts of 

843
00:47:53,500 --> 00:47:56,700
the entire Spectrum. 
Yeah, I think the full spectrum 

844
00:47:56,700 --> 00:48:01,100
is pretty critical and the the 
study seemed to show that you 

845
00:48:01,100 --> 00:48:05,800
can just the the effects are 
much stronger at lower doses 

846
00:48:06,100 --> 00:48:09,700
with the full-spectrum first 
isolate and so for your 

847
00:48:09,700 --> 00:48:12,600
listeners you know there's 
different forms of CBD out 

848
00:48:12,600 --> 00:48:16,100
there. 
Some are going to be you know, 

849
00:48:16,100 --> 00:48:21,600
just the CBD molecule completely
isolated on its own and then 

850
00:48:21,600 --> 00:48:27,500
there's other ones that Tain, 
the full bouquet of cannabinoids

851
00:48:27,500 --> 00:48:31,300
and terpenoids, which are the 
flavoring molecules at the 

852
00:48:31,300 --> 00:48:38,100
plants produce in the in the 
product and they found that 

853
00:48:38,500 --> 00:48:41,800
there's something called the 
Entourage effect where multiple 

854
00:48:41,800 --> 00:48:45,100
terpenes together combined with 
these cannabinoids, in the way 

855
00:48:45,100 --> 00:48:49,600
that the plant produces them 
tends to increase the Synergy of

856
00:48:49,600 --> 00:48:52,500
these compounds. 
So, one of the things that they 

857
00:48:52,500 --> 00:48:56,700
found Is that with isolate, you 
have to be very precise with the

858
00:48:56,700 --> 00:48:59,000
dosage. 
There's a window where not 

859
00:48:59,000 --> 00:49:01,700
enough doesn't work the right 
amount works but then you can 

860
00:49:01,700 --> 00:49:05,100
actually overshoot it and too 
much doesn't seem to have a 

861
00:49:05,100 --> 00:49:11,000
positive effect for some reason,
the Entourage effect, or taking 

862
00:49:11,000 --> 00:49:14,900
it with the full bouquet of 
terpenes and other cannabinoids 

863
00:49:15,300 --> 00:49:18,800
seems to make it so that it's 
you don't actually overshoot it.

864
00:49:18,800 --> 00:49:21,500
You can just keep using higher 
Doses and it still works. 

865
00:49:21,700 --> 00:49:24,600
You don't have that belt. 
Curved as much as you do with an

866
00:49:24,600 --> 00:49:27,000
isolate. 
So that's one of the issues with

867
00:49:27,000 --> 00:49:29,900
the market right now is that 
there's a lot of companies just 

868
00:49:29,900 --> 00:49:34,400
producing cheap isolate. 
That is kind of crap. 

869
00:49:34,600 --> 00:49:37,900
So I think it's really well 
worth knowing your Source 

870
00:49:37,900 --> 00:49:45,700
knowing the analysis of the 
product you're using and making 

871
00:49:45,700 --> 00:49:48,000
sure that you're getting 
something with, at least the 

872
00:49:48,000 --> 00:49:53,700
full range of terpenes. 
And it, the you Find some good 

873
00:49:53,700 --> 00:49:57,600
Blends that don't have th see in
them that the THC has been 

874
00:49:57,600 --> 00:50:00,000
removed. 
But you have to make sure that 

875
00:50:00,000 --> 00:50:04,900
the company is our that you that
are using a process that is not 

876
00:50:04,900 --> 00:50:07,900
heat or solvent-related that 
damages other terpenes. 

877
00:50:07,900 --> 00:50:09,900
And there are some that can do 
that. 

878
00:50:10,600 --> 00:50:13,300
But in general you know I'd say 
go for the full spectrum. 

879
00:50:13,300 --> 00:50:16,500
When you can, is there like a 
specific company or brand? 

880
00:50:16,500 --> 00:50:19,000
You recommend vouch for just 
being high quality. 

881
00:50:19,900 --> 00:50:22,100
Yeah. 
There's one that I really like 

882
00:50:22,100 --> 00:50:25,000
called on. 
The hemp or I'm a healing, a 

883
00:50:25,000 --> 00:50:27,600
MMA. 
They've got some really 

884
00:50:27,600 --> 00:50:30,200
excellent products. 
I'm an advisor to them full 

885
00:50:30,200 --> 00:50:34,500
disclosure but I agreed to come 
on because I took a look at 

886
00:50:34,500 --> 00:50:38,400
their supply chain transparency 
and their ethos and what they're

887
00:50:38,400 --> 00:50:41,900
doing in terms of really making 
sure that the product quality 

888
00:50:41,900 --> 00:50:44,600
comes first. 
And so I'm really confident and 

889
00:50:44,600 --> 00:50:48,700
what those guys do very nice. 
Is there any like I know we 

890
00:50:48,700 --> 00:50:51,600
talked about how, you know, 
certain individuals can have a 

891
00:50:51,600 --> 00:50:55,100
genetic makeup that is going to 
To potential adverse effects 

892
00:50:55,100 --> 00:50:58,400
from large dosages of THC for 
instance. 

893
00:50:58,400 --> 00:51:01,900
But that aside just in the, you 
know, CBD and other 

894
00:51:02,500 --> 00:51:07,400
cannabinoids, do you see any 
downside to having these in the 

895
00:51:07,400 --> 00:51:10,500
system? 
Like exogenously our first of 

896
00:51:10,500 --> 00:51:15,200
all, what could potentially lead
to a downregulated production in

897
00:51:15,200 --> 00:51:16,600
dodging? 
So that why do you think some 

898
00:51:16,600 --> 00:51:19,000
people are having deficiencies 
there? 

899
00:51:19,900 --> 00:51:22,100
Yeah, that's a really good 
question and I don't have a 

900
00:51:22,107 --> 00:51:24,100
great answer. 
For that, I think that that's 

901
00:51:24,100 --> 00:51:28,900
something to that the science 
will continue to elucidate and 

902
00:51:28,900 --> 00:51:30,500
have better answers for 
overtime. 

903
00:51:30,500 --> 00:51:34,000
You know. 
I think some people are 

904
00:51:34,000 --> 00:51:36,400
genetically prone to it, you 
know, looking at some of the 

905
00:51:36,400 --> 00:51:40,300
genes and then they're also our 
situation. 

906
00:51:40,300 --> 00:51:47,000
Say for example like there's 
typically low endocannabinoids 

907
00:51:47,000 --> 00:51:52,300
in depression and we know that 
trauma is a big factor in 

908
00:51:52,300 --> 00:51:54,900
depression. 
PTSD is another one where they 

909
00:51:54,900 --> 00:51:59,600
know that PTSD is associated 
with low circulating levels of 

910
00:51:59,600 --> 00:52:01,800
an and amide one of the main 
endocannabinoids. 

911
00:52:02,200 --> 00:52:06,700
So, it's likely that there's 
some epigenetic regulation 

912
00:52:06,700 --> 00:52:11,600
stemming from the body, trying 
to adapt to an acute, stressful 

913
00:52:11,600 --> 00:52:15,500
environment, and then not being 
able to turn off that signal and

914
00:52:15,500 --> 00:52:18,800
you could take that template and
apply it to probably a lot of 

915
00:52:18,800 --> 00:52:22,100
different disease States and 
conditions in terms of the body,

916
00:52:22,100 --> 00:52:26,600
trying To create an Adaptive 
response to something that ends 

917
00:52:26,600 --> 00:52:29,100
up getting stuck in a way, 
right? 

918
00:52:29,100 --> 00:52:34,000
And and becoming pathological 
and non-functional over time. 

919
00:52:34,400 --> 00:52:39,100
And so it's possible that, you 
know, adding the Endo cannot or 

920
00:52:39,100 --> 00:52:41,600
the cannabinoids into the system
can help kind of break that Loop

921
00:52:41,600 --> 00:52:44,400
in a way catch. 
And you mention the CBD kind of 

922
00:52:44,400 --> 00:52:48,700
helps basically four to five. 
That's that our own Indulgence 

923
00:52:48,700 --> 00:52:51,800
production can kind of ramp up 
so to speak. 

924
00:52:51,800 --> 00:52:54,400
Is that going to be pretty much?
True across the board. 

925
00:52:54,400 --> 00:52:56,000
Sir, some more than others. 
I'm sure. 

926
00:52:56,000 --> 00:52:58,200
But like, CBD in general is 
going to be just pretty 

927
00:52:58,200 --> 00:53:01,200
effective at allowing your body 
to build up that natural 

928
00:53:01,200 --> 00:53:03,500
production. 
Yeah, that's right. 

929
00:53:03,500 --> 00:53:07,100
And for certain people that may 
be more impactful, you know, it 

930
00:53:07,100 --> 00:53:10,100
for other people. 
Their problem might not be 

931
00:53:10,100 --> 00:53:13,800
stemming from a low levels of 
endocannabinoids at all, right? 

932
00:53:13,800 --> 00:53:18,300
Like in the case of, you know, 
something like obesity, where 

933
00:53:18,600 --> 00:53:22,200
these probe there people are 
probably already having access 

934
00:53:22,200 --> 00:53:24,000
levels. 
Is of an and amide or other 

935
00:53:24,000 --> 00:53:26,800
cannabinoids. 
So, you know, it kind of depends

936
00:53:26,800 --> 00:53:30,500
on just what the person's 
Baseline is when they're adding 

937
00:53:30,500 --> 00:53:32,600
these things in. 
And to answer your question in 

938
00:53:32,600 --> 00:53:37,000
terms of downsides, there's 
really not a lot of long-term 

939
00:53:37,700 --> 00:53:41,000
understanding, but at least in 
the short term right now, it 

940
00:53:41,000 --> 00:53:44,800
seems like there's very low down
side to CBD on its own. 

941
00:53:45,400 --> 00:53:47,600
Is there like a like a test 
where you can get blood? 

942
00:53:47,600 --> 00:53:50,100
Work drawn to see where you may 
be deficient with these 

943
00:53:50,100 --> 00:53:52,600
cannabinoids is like a getting a
cholesterol panel. 

944
00:53:53,300 --> 00:53:54,800
Well, how do you go about? 
Testing this? 

945
00:53:55,300 --> 00:53:58,600
Yeah, right now, the Gen-X are 
probably the best way to do it 

946
00:53:59,400 --> 00:54:01,200
as someone who's interested in 
it. 

947
00:54:01,400 --> 00:54:04,700
There's not really a 
commercially available tests you

948
00:54:04,700 --> 00:54:09,000
know, this would mostly be 
University Research centers that

949
00:54:09,000 --> 00:54:12,200
are looking at and do 
cannabinoid levels but the 

950
00:54:12,200 --> 00:54:15,100
genetics act as a pretty good 
proxy for understanding that. 

951
00:54:15,300 --> 00:54:18,100
Gotcha, gotcha, very cool, man. 
I'm learning a ton. 

952
00:54:18,600 --> 00:54:19,700
What? 
What? 

953
00:54:19,700 --> 00:54:21,500
Just kind of develop here in 
recap? 

954
00:54:21,500 --> 00:54:24,500
What are you Taking in going 
with four with this knowledge. 

955
00:54:24,500 --> 00:54:25,600
That what are you excited about 
now? 

956
00:54:25,600 --> 00:54:27,900
What's on the horizon? 
What are you predominantly 

957
00:54:27,900 --> 00:54:34,800
focusing on in the future here? 
Yeah, so I am about to launch a 

958
00:54:34,800 --> 00:54:38,700
practitioner training for people
that are interested in running 

959
00:54:38,700 --> 00:54:40,700
and do cannabinoid genetics for 
their clients. 

960
00:54:40,800 --> 00:54:44,800
So if anyone is listening and 
your coach or practitioner and 

961
00:54:44,800 --> 00:54:47,500
or thinking that, it'd be nice 
to be able to provide more 

962
00:54:47,500 --> 00:54:49,300
precise answers for your 
clients. 

963
00:54:49,500 --> 00:54:51,100
You know, how they respond to 
cannabis? 

964
00:54:51,100 --> 00:54:52,600
Is this something that's right 
for them? 

965
00:54:53,900 --> 00:54:57,400
People can go to have a website 
set up at canadienne. 

966
00:54:57,400 --> 00:55:02,400
A DOT education, CA n, n DN, a--
dot education and I can sign up 

967
00:55:02,400 --> 00:55:06,200
for the list and I'll be 
updating people is that's 

968
00:55:06,200 --> 00:55:08,200
available in the next couple 
months. 

969
00:55:08,500 --> 00:55:13,500
And so I've been working a lot 
on that and, you know, mostly 

970
00:55:13,700 --> 00:55:17,100
that and seeing clients and 
helping people move towards 

971
00:55:17,100 --> 00:55:18,800
Optimal Health and whatever way 
I can. 

972
00:55:19,000 --> 00:55:23,600
But yeah, the the practitioner 
training and getting People set 

973
00:55:23,600 --> 00:55:27,600
up to be able to use this info. 
It's kind of my big project 

974
00:55:27,600 --> 00:55:29,900
right now. 
Do you do like, like one-off 

975
00:55:29,900 --> 00:55:32,300
consultation calling someone has
their raw genetic data? 

976
00:55:32,300 --> 00:55:34,500
Can they like schedule a 
consultation code with you? 

977
00:55:35,100 --> 00:55:37,300
Yeah. 
Yeah, I offer free 30-minute 

978
00:55:37,300 --> 00:55:39,600
consultation, to anyone that's 
interested. 

979
00:55:39,600 --> 00:55:41,200
In just learning how we could 
work together. 

980
00:55:41,500 --> 00:55:44,000
You know, I really like to take 
a little bit of time to 

981
00:55:44,000 --> 00:55:47,700
understand what someone's needs 
are and look at different 

982
00:55:47,700 --> 00:55:51,600
options as far as genetic 
analysis or ongoing coaching. 

983
00:55:51,600 --> 00:55:55,200
So yeah, if someone Their 
genetics feel free to reach out 

984
00:55:55,200 --> 00:55:59,700
to me and I also do have a test 
that I prefer to use. 

985
00:56:00,000 --> 00:56:04,900
That is really good with privacy
and data ownership and so if 

986
00:56:04,900 --> 00:56:07,100
anyone's listening and you're 
like, you know, I would you like

987
00:56:07,100 --> 00:56:10,000
to do this but I've been kind of
concerned that 23andMe is going 

988
00:56:10,000 --> 00:56:13,600
to sell my data. 
We have a private lab that all 

989
00:56:13,600 --> 00:56:16,600
of that is out of the picture 
and what is the website for 

990
00:56:16,600 --> 00:56:18,900
that. 
That's just my website. 

991
00:56:18,900 --> 00:56:21,800
Digital dash Krantz.com, nice 
will shoot man. 

992
00:56:21,800 --> 00:56:24,800
I've got on my Raw data may just
linked up with you and we can 

993
00:56:25,100 --> 00:56:27,500
record a follow-up episode just 
going over the date or something

994
00:56:27,500 --> 00:56:28,400
like that. 
I don't know if they've been 

995
00:56:28,400 --> 00:56:30,700
interesting. 
Yeah, that'd be cool. 

996
00:56:30,700 --> 00:56:34,000
I'd love to, you know, add more 
layers to your understanding of 

997
00:56:34,000 --> 00:56:36,600
your body and be cool to go over
it. 

998
00:56:36,800 --> 00:56:38,800
Awesome, awesome. 
Well, David, I certainly do 

999
00:56:38,800 --> 00:56:40,800
appreciate the time. 
I like said I learned quite a 

1000
00:56:40,808 --> 00:56:44,000
bit and let's definitely keep in
touch because it's, this does 

1001
00:56:44,000 --> 00:56:46,900
fascinate me for sure? 
Yeah, well, thank you, I really 

1002
00:56:46,900 --> 00:56:48,900
enjoyed chatting with you. 
And really enjoyed all the 

1003
00:56:48,900 --> 00:56:51,300
questions you asked just really,
really spot-on. 

1004
00:56:51,700 --> 00:56:53,000
Awesome will keep going. 
You doing, man? 

1005
00:56:53,000 --> 00:56:55,000
I appreciate you. 
Thanks man. 

1006
00:56:55,100 --> 00:56:55,700
Likewise
